Gene responsible for the onset of aging
Mayo Clinic researchers have discovered a gene responsible for the onset of aging, including age-related disorders such as infertility, reproductive problems and cataracts.
This research, conducted in genetically modified mice, is promising in helping physicians understand and treat the same disorders in humans.
"Darren Baker in our laboratory found that mutant mice with low amounts of BubR1 protein live five times shorter than normal mice. They also develop a variety of age-related disorders at a very young age," says lead investigator Jan van Deursen, Ph.D., of the Mayo Clinic Departments of Pediatric and Adolescent Medicine, and Biochemistry and Molecular Biology.
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